The subspecies corynebacterium afermentans afermentans was originally described and validly published by riegel et al. Corynebacterium amycolatum was the predominant species 35. Corynebacterium diphtheriae is the etiological agent of diphtheria, an upper respiratory disease mainly affecting children. The liver abscess penetrated through the diaphragm to cause pleural. Corynebacterium afermentans, a species recently identified, has previously been isolated from human blood cultures. The genus corynebacterium and other medically relevant. Jun 14, 2019 c diphtheriae infection is typically characterized by a local inflammation, usually in the upper respiratory tract, associated with toxinmediated cardiac and neural disease. Pdf the isolation of corynebacterium coyleae from clinical. May 27, 2019 corynebacterium n a taxonomic genus within the family corynebacteriaceae grampositive bacteria, including the species that causes diphtheria. Competent microbiological analysis can easily identify the corynebacterium species capable of causing human illness. We report the case of a previously healthy 39yearold man who developed a brain abscess and a liver abscess due to corynebacterium afermentans subsp. Urinary tract infection due to corynebacterium urealyticum.
A unique coryneform bacterium was isolated from a patient with bacterial vaginosis. A prerequisite for the development of recombinant dna techniques for amino acidproducing corynebacterium glutamicum was the identification of endogenous plasmids santamaria et al. Mar 05, 2014 a handful of the other corynebacterium species can sicken people who are severely immunocompromised due to other illnesses or due the side effects of medications used to treat other conditions, or due to advanced age. Oct 10, 2018 n 17, corynebacterium striatum n, and corynebacterium afermentans n11. Corynebacterium definition, rodshaped bacteria of the genus corynebacterium, many species of which are pathogenic. Therefore, we propose a new species, corynebacterium afermentans sp. The investigation of numerous involved hairs of two patients in a scanning electron microscope reveals that the socalled trichomycosis axillaris is a hair disease of bacterial origin which leads to considerable destruction of the hair cuticle and of the superficial hair cortex. Corynebacterium previously eubacterium, now actinobaculum cystitidis synonyms, corynebacterium previously eubacterium, now actinobaculum cystitidis pronunciation. Hair destroying growth of corynebacterium tenuis in the so. Corynebacterium definition and meaning collins english. An efficient succinic acid production process in a. The isolation of corynebacterium coyleae from clinical samples.
Corynebacterium is a genus of bacteria that are grampositive and aerobic. Twenty corynebacterium strains were isolated and identified as corynebacterium striatum n 7, corynebacterium amycolatum n 7, c. Corynebacterium mucifaciens in an immunocompetent patient. Dec 17, 2010 corynebacterium mucifaciens has been mainly isolated from skin, blood and from other normallysterile body fluids. The corynebacterium diphtheriae nctc 129 genome is 2,488,625 bp in length and has an. Although most species are harmless saprophytes and many are part of the normal human skin and mucous membrane flora, corynebacterium diphtheriae, the agent of diphtheria, and corynebacterium jeikeium and corynebacterium urealyticum have been identified as causative agents of infections in compromised human hosts. Corynebacterium species rarely cause orthopedic infections. Corynebacterium and other medically relevant coryneform. Management of cri in neutropenic patients is based on the same principles as treatment of fever of unknown origin fuo.
Corynebacterium urealyticum, corynebacterium striatum, corynebacterium amycolatum. It belongs to the high gc content gram positives, also called actinobacteria. Corynebacterium suis definition of corynebacterium suis by. The yellowpigmented, slightly lipophilic, oxidative, ureahydrolyzing bacterium could be phenotypically readily differentiated from the other members of the genus corynebacterium. Annotations api oai service bulk downloads developers forum help. Specifically, they are commonly isolated from guinea pig conjunctiva. Species identities and antimicrobial susceptibilities of.
Corynebacterium previously eubacterium, now actinobaculum. Chemotaxonomical investigations demonstrated that the unknown bacterium belonged to the genus corynebacterium. In one study, 27 out of 30 clinically normal pet guinea pigs grew corynebacterium spp. The subsequent construction of cloning vectors carrying antibiotic resistance genes as selectable markers and the development of methods enabling an efficient dna transfer provided a. Corynebacterium afermentans afermentans namesforlife. Corynebacterium article about corynebacterium by the free. Corynebacterium urealyticum formerly known as corynebacterium group d2 is a grampositive bacillus with special tropism for the urinary tract.
Each of the remaining 19 species comprised of less than 10% of the isolates. Corynebacterium glutamicum, a highgc content, grampositive soil bacterium, is an important organism for the industrial production of amino. Description of the bacterial genus corynebacterium. All isolates have been tested for antibiotic susceptibility by standardized disc diffusion method and. Other species are recognized as opportunistic pathogens, and have been isolated from diverse. Corynebacterium kutscheri is a grampositive coryneform clubshaped bacterium which can be found in soil, sewage, and marine environments, and has been explored for possible utility of bioremediation of oil spills oyetibo et al. Corynebacterium ammoniagenes brevibacterium ammoniagenes. Corynebacterium pseudotuberculosis pneumonia in a veterinary. Bratcher, in principles and practice of pediatric infectious diseases fifth edition, 2018. Corynebacterium definition of corynebacterium by medical. In one series, corynebacterium jeikeium and corynebacterium striatum were significantly overrepresented in the group with true infection, whereas corynebacterium afermentans was pre likely garbage.
Antimicrobial susceptibility testing for corynebacterium. Table 1 medically relevant corynebacterium speciesa taxonb infection or site recovered in humans or animalsc c. Social security administration public data, the first name corynebacterium was not present. Succinic acid was shown to be efficiently produced at highcell density under oxygen. Taxonomic study of corynebacterium group anf1 strains.
Corynebacterium jeikeium, formerly known as centers for disease control and. Corynebacterium diphtheriae is a rodshaped, gram positive, non sporeforming, and nonmotile bacterium. And the real deals were usually prosthetic valve endocarditis and had only one positive blood culture pubmed. Corynebacterium afermentans cdc group anf 1 an aerobic, non spore forming, grampositive coccobacillus that produces cream or white colonies. Phylogeny of the genus corynebacterium deduced from analyses. Neutropenia, comorbidity, clinical features, catheter site, samples origin, corynebacterium species. Identification of corynebacterium amycolatum and other. Central venous catheterrelated infections caused by. A genus of grampositive, straight or slightly curved rods in the coryneform group of bacteria. By 16s rrna gene sequencing, corynebacterium afermentans is closely related to 98% identity with to corynebacterium coyleae and corynebacterium mucifaciens but differs. It is possible the name you are searching has less than five occurrences per year. These infections were ssscaused by corynebacterium amycolatum and other nondiphtherial corynebacteria.
Corynebacterium definition of corynebacterium by merriam. Help pages, faqs, uniprotkb manual, documents, news archive and biocuration projects. Three strains of c diphtheriae are recognized, in decreasing order of virulence. This bacterium can synthesize struvite stones because of its strong urease activity and develop encrusted pyelitis and cystitis. Corynebacterium parvum article about corynebacterium parvum. In six patients, the isolates were considered as clinically significant, three definite. Pdf fourteen corynebacterium coyleae isolates were recovered from 12 inpatients during a 5years. Fourteen corynebacterium coyleae isolates were recovered from 12 inpatients during a 5years period. It has rarely been described as a human pathogen since its description. In the case of renal transplant recipients, this infection has been described in association with obstructive. They are bacilli rodshaped, and in some phases of life they are, more particularly, clubshaped, which inspired the genus name coryneform means clubshaped they are widely distributed in nature in the microbiota of animals including the human. Corynebacterium amycolatum is one of the diphtheroids most often isolated from clinical samples 3, 11. Pdf corynebacterium species causing urinary tract infections. Corynebacterium bernard major reference works wiley.
Identification of corynebacterium bovis and other coryneforms. Corynebacterium glutamicum is a soildwelling gram positive bacterium. Pdf fourteen corynebacterium coyleae isolates were recovered from 12 in patients during a 5years. Plasmids in corynebacterium glutamicum and their molecular.
Corynebacterium kutscheri an overview sciencedirect topics. Corynebacterium diphtheriae is the aetiological agent of diphtheria. Corynebacterium glutamicum bacteriology lmu munich. The zoonotic agents corynebacterium pseudotuberculosis the cause of caseous lymphadenitis primarily in sheep and goats, transmitted to humans by contact with diseased animals and c. Crisprcpf1 assisted genome editing of corynebacterium. The rates of susceptibility of corynebacteria isolated from orthopedic.
They are bacilli rodshaped, and in some phases of life they are, more particularly, clubshaped, which inspired the genus name coryneform means clubshaped. Corynebacterium suis synonyms, corynebacterium suis pronunciation, corynebacterium suis translation, english dictionary definition of corynebacterium suis. Corynebacterium definition is any of a genus corynebacterium of usually grampositive nonmotile bacteria that occur as irregular or branching rods and include the causative agent of diphtheria. Corynebacterium species, which are recognized as members of the normal human flora, are isolated from the skin, mucous membranes, and gastrointestinal tract. These strains all produce an identical toxin, but the. The virulence factors most specifically diphtheria toxin have been studied extensively and are well understood. Pdf corynebacterium species rarely cause orthopedic infections.
Corynebacterium bovis based on colony morphology and growth in the. Although frequently dismissed as contaminants in clinical specimens, corynebacteria are recognized more often as pathogens. In most cases of communityacquired pneumonia cap, an etiologic agent is not determined. Corynebacterium pseudotuberculosis is a facultative anaerobic pleomorphic grampositive rod first ide. The microbe is a well known pathogen in veterinary medicine infecting ungulates, predominantly sheep and goats, although horses, cattle, and deer may also be infected 23. It includes both pathogenic and nonpathogenic organisms, which are widely distributed in nature. Corynebacterium urealyticum, corynebacterium striatum, corynebacterium amycolatum, andcorynebacterium jeikeium predominated, accounting for 63% of all isolates. Microbiological and biochemical origins of human axillary odour. We herein report the first case of cavitary pneumonia due to c. Over a 14month period, 415 clinical isolates of coryneform grampositive rods were recovered from various sources and identified to the species level according to recent identification schemes. Corynebacterium diphtheriae is the bacterium that causes the disease diphtheria.1008 1114 224 1157 121 1278 235 192 1116 1235 1250 1504 622 790 1223 894 1416 344 292 501 544 1410 542 1212 1484 1007 647 909 276 1497 807 1349 731 628 1514 1100 380 1191 30 944 1321 307 1176 1225 445 1185 1033 1313